GENE THERAPY VECTOR

CLINICAL CENTER GENOTYPING CENTER
Information regarding Cystic Fibrosis, the types of research being performed to finds its cure.  Learn more about gene therapy, and treatments for Cystic Fibrosis as well as volunteering opportunities.
The Center has many research laboratories dedicated to finding a cure for Cystic Fibrosis.  Meet the different lab directors, their lab members and the laboratories particular focus.
A complete list of publications from the Centers lab directors that are related to Cystic Fibrosis.
Apply for open positions at the Cystic Fibrosis Research Development Center.
Visit other websites of organizations and associations affiliated with Cystic Fibrosis.
Letter from the Director addressing the Centers continued plan for the future.
 
 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
 

 

 

Beth L. Laube

Beth Home|Publications|Lab Members 

 

 

Beth L. Laube

Associate Professor
The Johns Hopkins University School of Medicine
Department of Pediatrics
Division of Pediatric Pulmonary
Baltimore, MD
600 North Wolfe Street
Baltimore, Maryland 21287-2533

blaube@jhmi.edu 
 

 

Beth Laube

       
  Publications
 

Laube, B.L.  Advances in treating diabetes with aerosolized insulin.  Diabetes Technology and Therapeutics 4:515-518, 2002.

 

Laube, B.L., Curbow, B.A., Costello, R.F., Fitzgerald, S.T.  A pilot study examining the relationship between stress and serum cortisol levels in women with asthma.  Respiratory Medicine 96:823-828, 2002.

 
Beck, S.E., Laube, B.L., Barberena, C.I., Fischer, A.C., Adams, R.J., Chesnut, K., Flotte, T.R., Guggino, W.B.  Deposition and expression of aerosolized rAAV vectors in the lungs of Rhesus Macaques.  Molecular Therapy 6:546-554, 2002.
 

Laube, B.L., Lin, T-C., Valleteau, A., Dalby, R.N., Diemer, F.B., Togias, A.G.  Complete protection against bronchoconstrictor response to allergen challenge with nedocromil sodium aerosol in patients with asthma.  J. Aerosol Med. 15:415-425, 2002.

 

Laube, B.L., Curbow, B.A., Fitzgerald, S.T., Spratt, K.  Early pulmonary response to allergen is attenuated during acute emotional stress in women with asthma. Eur. Resp. J. 22:613-618, 2003.

 

Fischer, A.C., Beck, S.E., Barberena, C.I., Laube, B.L., Askin, F.B., Guggino, S.E., Adams, R.J., Flotte, T.R., Guggino, W.B.  Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques. Molecular Therapy 8:918-26, 2003.

 

Laube, B.L., Karmazyn, Y., Clark, A.R., Newhouse, M.  Targeted Aerosol Delivery in Healthy Human Lungs. In: Dalby, R.N., Byron, P.R. and Farr, S.T., eds. Respiratory Drug Delivery IX. Raleigh, N.C. Serentek Press, Inc. pp. 525-527, 2004.

 

Laube, B.L., Geller, D., Lin,T-C., Dalby, R., Diener-West, M., Zeitlin P.L.  Positive expiratory pressure changes aerosol deposition in the lungs of patients with cystic fibrosis. Respiratory Care 50:1438-1444, 2005.

 

Guo, Y., Laube, B., Dalby, R. The effect of formulation variables and breathing patterns on the site of nasal deposition in an anatomically correct model.  Pharmaceutical Research 22:1871-1878, 2005.

 

Laube, B.L. The expanding role of aerosols in systemic drug delivery, gene therapy and vaccination. Respiratory Care 50:1162-1176, 2005.

 

Suman, J.D., Laube, B.L., Dalby, R. Validity of In Vitro Tests on Aqueous Spray Pumps as Surrogates for Nasal Deposition, Absorption and Biologic Response. J. Aerosol Med. In Press, 2006.

 

McGrath-Morrow, S.A., Laube, B.L.,Tzou, S.C., Cho, C., Cleary, J., Kimura, H., Rose, N.R., Caturegli, P.  IL-12 over-expression in mice as a model for Sjogren lung disease. Am. J. Physiol. Lung. Cell Mol. Physiol. In Press, 2006.

 

Laube, B.L. Devices for aerosol delivery to treat sinusitis. J. Aerosol Med. In Press, 2006.

615 N. Wolfe Street, Baltimore, MD 21205