GENE THERAPY VECTOR

 CLINICAL CENTER GENOTYPING CENTER
Information regarding Cystic Fibrosis, the types of research being performed to finds its cure. Learn more about gene therapy, and treatments for Cystic Fibrosis as well as volunteering opportunities.
The Center has many research laboratories dedicated to finding a cure for Cystic Fibrosis. Meet the different lab directors, their lab members and the laboratories particular focus.
A complete list of publications from the Centers lab directors that are related to Cystic Fibrosis.
Apply for open positions at the Cystic Fibrosis Research Development Center.
Visit other websites of organizations and associations affiliated with Cystic Fibrosis.
Letter from the Director addressing the Centers continued plan for the future.
 
 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
 
 

 
 

Garry Richard Cutting, M.D.

Garry Home|Publications|Book Chapters | Lab Members 

   

Garry Richard Cutting, M.D.
Professor of Pediatric and Medicine
Aetna/U.S. Healthcare Professor of Medical Genetics
Director, Residency and Postdoctoral Training Program in Medical Genetics
Director, DNA Diagnostic Laboratory
The Johns Hopkins University School of Medicine
Baltimore, MD 21205
Email: gcutting@jhmi.edu
 

Garry Cutting
 

        
  Publications
 

Zeitlin PL, Lu L, Hwang TC, Rhim J, Craig R, Cutting GR, Stetten G, Kieffer KA, Guggino WB.  A Cystic Fibrosis bronchial epithelial cell line:  Immortalization by Adeno-12 SV-40 infection.  Am J Resp Cell and Mol Biol (1991), 4:313-319.
 
Reiss J, Cooper DN, Bal J, Slomski R, Cutting GR, Krawczak M.  Discrimination between recurrent mutation and identity by descent:  application to point mutations in exon 11 of the CFTR gene.  Human Genetics (1991), 87:457-461.
 

Francomano CA,Cutting GR, McCormick MK, Chu ML, Timpl R, Hong HK, Antonarakis SE.  The COL6A1 and COL6A2 genes exist as a gene cluster and detect highly informative DNA polymorphisms in the telomeric region of human chromosome 21q.  Human Genetics (1991), 87:162-166.

 

Chu C-S, Trapnell BC, Murtagh JJ Jr, Moss J, Dalemans W, Jallat S, Mercenier A, Pavirani A, Lecocq J-P, Cutting G, Guggino WB and Crystal RG.  Variable deletion of exon 9 coding sequences in Cystic Fibrosis gene mRNA transcripts in normal bronchial epithelium.  EMBO J. (1991), 10:1355-1363.
 
Graham CA, Goon PKC, Hill AJM, Cutting GR, Curristin S, Nevin NC. Identification of a  new mutation (R297Q) in exon 7 of the CFTR gene in a Northern Ireland family. J Med Genet (1991) 28:571.
 

Hamosh A, Trapnell BC, Zeitlin PL, Montrose-Rafizadeh C, Rosenstein BJ, Crystal RG, and Cutting GR.  Severe deficiency of CFTR mRNA carrying nonsense mutations R553X and W1316X in respiratory epithelial cells of patients with cystic fibrosis.  J Clin Invest (1991) 88:1880-1885.
 

Dietz HC, Cutting GR, Pyeritz RE, Maslen CL, Sakai LY, Corson GM, Puffenberger EG, Hamosh A, Nanthakumar EJ, Curristin SM, Stetten G, Meyers DA, Francomano CA.  Marfan syndrome caused by a recurrent denovo missense mutation in the fibrillin gene.  Nature (1991), 352:337-339.
 
Cutting GR, Lu L, O'Hara B, Kasch LM, Donovan D, Shimada S, Antonarakis SE, Guggino WB, Uhl GR, Kazazian H Jr.  Cloning of the gamma-aminobutyric acid (GABA) rho1 cDNA:  A GABA receptor subunit highly expressed in the retina.  Proc Natl Acad Sci (USA) (1991), 88:2673-2677.
 
Dietz HC, Pyeritz RE, Kendzior RJ, Puffenberger EG, Corson G, Sakai LY, Francomano CA, Cutting GR. Marfan phenotype variability in a family segregating a missense mutation in the EGF-like motif of the fibrillin gene. J Clin Invest (1992), 89:1674-1680.
 
Dietz HC, Saraiva J, Pyeritz RE, Cutting GR, Francomano CA.  Clustering of fibrillin 15       missense mutations causing the Marfan syndrome at residues with significance for calcium     binding in EGF-like domains.  Hum Mutation (1992), 1:366-374. 
 
Abeliovich D, Lavon IP, Lerer I, Cohen T, Springer C, Avital A, Cutting GR.  Screening for five mutations detects 97% of CF chromosomes and predicts a carrier frequency of 1:29 in the Jewish Ashkenazi populations.  Am J Hum Genet (1992) 51:951-956.
 

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