Garry
Richard Cutting, M.D.
Professor of Pediatric and Medicine
Aetna/U.S. Healthcare Professor of Medical Genetics
Director, Residency and Postdoctoral Training Program in
Medical Genetics
Director, DNA Diagnostic Laboratory
The Johns Hopkins University School of Medicine
Baltimore, MD 21205
Email:
gcutting@jhmi.edu
Garry
Cutting
Publications
Chu
C-S, Trapnell BC, Curristin SM, Cutting GR,
Crystal RG. Extensive post-transcriptional deletion
of the coding sequences for part of nucleotide-binding
fold 1 in respiratory epithelial mRNA transcripts of
the cystic fibrosis transmembrane conductance regulator
gene is not associated with the clinical manifestations
of cystic fibrosis. J Clin Invest (1992) 90,785-790.
Cozens AL, Yezzi MJ, Yamaya M, Steiger D, Wagner JA,
Garber SS, Chin L, Simon EM, Cutting GR,
Gardner P, Friend DS, Basbaum CB, Gruenert DC.
A transformed human epithelial cell line that retains
tight junctions post crisis. In Vitro Cell Dev
Biol (1992), 28A:735-744.
Cutting GR, Curristin SM, Nash E, Rosenstein
BJ, Lerer I, Abeliovich D, Hill A, Graham C. Analysis
of four diverse population groups indicates that a subset
of cystic fibrosis mutations occur in common among Caucasians.
Am J Hum Genet (1992), 50:1185-1194.
Cutting GR,
Curristin S, Zoghbi H, O'Hara B, Seldin MF, Uhl GR.
Identification of a putative gamma aminobutyric acid
(GABA) receptor subunit rho2 cDNA and colocalization
of the genes encoding rho2 (GABBR2) and rho1
(GABRR1) to human chromosome 6q14-q21 and mouse chromosome
4. Genomics (1992), 12:801-806.
Hamosh A, King TM, Rosenstein BJ, Corey M, Levison H,
Durie P, Lap-Chee T, McIntosh I, Keston M, Brock DJH,
Macek M Jr, Zemkova D, Krasnicanova H, Vavrova V, Macek
M Sr, Golder N, Schwarz MJ, Super M, Watson EK, Williams
C, Bush A, O'Mahoney SM, Humphries P, DeArce MA, Reis
A, Burger J, Stuhrmann M, Schmidtke J, Wulbrand U, Dork
T, Tummler B, Cutting GR. Cystic fibrosis
patients bearing both the common missense mutation gly→asp
at codon 551 and the ∆F508 mutation are clinically
indistinguishable from ∆F508 homozygotes, except
for decreased risk of meconium ileus. Am J Hum Genet
(1992) 51:245-250.
Hamosh A, Rosenstein BJ,Cutting GR.
CFTR nonsense mutations G542X and W1282X associated
with severe reduction of CFTR mRNA in respiratory epithelial
cells. Hum Mol Genet (1992) 1:542-544.
Lerer I, Sagi M, Cutting GR, Abeliovich
D. Cystic fibrosis mutations in Jewish patients:
deltaF508 and G542X. J Med Genet (1992),
29:131-133.
Macek, M, Hamosh, A, Kiesewetter S, McIntosh, I, Rosenstein,
BJ, Cutting GR. Identification
of a novel nonsense mutation (L88X) in exon 3 of the
CFTR gene on a native Korean cystic fibrosis chromosome.
Hum Mutation (1992) 1:501-502.
Montrose-Rafizadeh
C, Blackmon DL, Hamosh A, Oliva MM, Hawkins AL, Curristin
SM, Griffin CA, Yang VW, Guggino WB, Cutting
GR, Montrose MH. Regulation of CFTR gene transcription
and alternative RNA splicing in a model of developing
intestinal epithelium. J Biol Chem (1992) 267:299-305.
Shimada S, Cutting GR, Uhl GR.
GABA A or C receptor?: GABA rho1 receptor
RNA induces bicuculline, barbiturate and benzodiazepine-insensitive
GABA responses in Xenopus oocytes. Mol Pharm (1992),
41:683-687.
Zeitlin PL, Crawford I, Lu L, Woel S, Cohen ME, Donowitz
M, Montrose M, Hamosh A, Cutting GR,
Gruenert D, Huganir R, Maloney P, Guggino WB.
CFTR protein expression in primary and cultured epithelia.
Proc Natl Acad Sci (USA) (1992), 89:344-347.
