GENE THERAPY VECTOR

 CLINICAL CENTER GENOTYPING CENTER
Information regarding Cystic Fibrosis, the types of research being performed to finds its cure. Learn more about gene therapy, and treatments for Cystic Fibrosis as well as volunteering opportunities.
The Center has many research laboratories dedicated to finding a cure for Cystic Fibrosis. Meet the different lab directors, their lab members and the laboratories particular focus.
A complete list of publications from the Centers lab directors that are related to Cystic Fibrosis.
Apply for open positions at the Cystic Fibrosis Research Development Center.
Visit other websites of organizations and associations affiliated with Cystic Fibrosis.
Letter from the Director addressing the Centers continued plan for the future.
 
 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
 
 

 
 

Pamela L. Zeitlin, M.D., Ph.D.

Pam Home | Publications | Book Chapters | Lab Members

 

 

Pamela L. Zeitlin, M.D., Ph.D.
Professor of Pediatrics
The Johns Hopkins University School of Medicine
Baltimore, MD 21205
Email: pzeitlin@jhmi.edu

 

Pamela Zeitlin
 

        
  Publications
 

Zeitlin PL, Chu S, Conrad C, McVeigh U, Ferguson K, Flotte TR, and Guggino WB.  Alveolar stem cell transductin by an adeno-associated viral vector.  Gene Therapy 2:623-631, 1995.
 
Murray CM, Morales MM, Flotte TR, McGrath-Morrow SA, Guggino WB, and Zeitlin PL.  C1C2: A developmentally-dependent chloride channel expressed in the fetal lung and downregulated after birth.  Am. J. Respir. Cell Mol. Biol. 12:597-604, 1995.
 
April MA, Tunkel DE, Decelie-Germana J, Zeitlin PL, and Zinreich SJ.  Computed tomography (CT) scan findings of the paranasal sinuses in cystic fibrosis.  Am. J. Rhino. 9(5):277-280, 1995.
 

Guay-Broder C, Jacobson KA, Barnoy S, Cabantchik ZI, Guggino WB, Zeitlin PL, Turner RJ, Vergara L, Eidelman O, and Pollard HB.  A! receptor antagonist8-cyclopentyl-1,3-dipropyl xanathine selectively activates chloride efflux from human epithelial and mouse fibroblast cell lines expressing the cystic fibrosis transmembrane regulator delta F508 mutation.  Biochemistry 34(28):9079-9087, 1995.
 
Murray CB, Chu S, and Zeitlin PL.  Gestational and tissue-specific regulation of C1C-2 chloride channel expression.  Am. J. Physiol 271 (Lung Cell. Mol. Biol. 15):L829-L837, 1996.
 

Chu S, Murray CB, Liu MM, and Zeitlin PL.  A short C1C-1 mRNA transcript is produced by exon skipping.  Nucleic Acids Research 24(17):3453-3457, 1996.
 
Rubenstein RC, McVeigh U, Flotte TR, Guggino WB, and Zeitlin PL.  CFTR gene transduction in neonatal rabbits using an adeno-associated virus (AAV) vector.  Gene Therapy 4:382-392, 1997.
 
Chu S, and Zeitlin PL.  Alternative mRNA splice variants of the C1C-2 chloride channel gene are expressed in lung: genomic sequence and organization of C1C-2.  Nucleic Acids Research 25:4153-4159. 1997.
 
Rubenstein RC, Egan ME, and Zeitlin PL.  In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing DF508-CFTR.  J. Clin. Invest. 100:2457-2465, 1997.
 
Rosenstein BJ, and Zeitlin PL.  Cystic Fibrosis.  Lancet 351:277-282, 1997.
 
Schweibert EM, Cid-Soto LP, Stafford D, Carter M, Blaisdell C, Zeitlin PL, Guggino WB, and Cutting GC.  Analysis of C1C-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells.  Proc. Nat. Acad. Sci. USA 95:3879-3884, 1998.
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