GENE THERAPY VECTOR

 CLINICAL CENTER GENOTYPING CENTER
Information regarding Cystic Fibrosis, the types of research being performed to finds its cure. Learn more about gene therapy, and treatments for Cystic Fibrosis as well as volunteering opportunities.
The Center has many research laboratories dedicated to finding a cure for Cystic Fibrosis. Meet the different lab directors, their lab members and the laboratories particular focus.
A complete list of publications from the Centers lab directors that are related to Cystic Fibrosis.
Apply for open positions at the Cystic Fibrosis Research Development Center.
Visit other websites of organizations and associations affiliated with Cystic Fibrosis.
Letter from the Director addressing the Centers continued plan for the future.
 
 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
 
 

 
 

Sandra Elizabeth Guggino

Sandra Home | Research Interests | Publications | Book Chapters | Lab Members

   

Sandra Elizabeth Guggino
Associate Professor
Division of Gastroenterology
Department of Medicine
The Johns Hopkins University School of Medicine
929 Ross Research Building
720 Rutland Avenue
Baltimore, MD 21205
Email: sguggino@jhmi.edu

 

Sandra Guggino
 

        
  Publications
 

Hwang, T-CH, SE Guggino, WB Guggino.  Direct modulation of secretory chloride channels by arachidonic acid and other cis-unsaturated fatty acids.  Proc. Natl.  Acad. Sci. USA 87:5706-5609, 1990.

 

Lin, M, AC Nairn and SE Guggino.  Cyclic GMP dependent protein kinase regulation of a chloride channel in T84 cells.  Am. J. Physiol. 262 (Cell Physiol. 31):C1304-C1372, 1992

 
Farrington, H, F Mendelsohn, S Chan, L Reinlib, SE Guggino. Strychnine binding proteins in intestinal cells: Novel brucine binding sites with binding affinities for alkaloids. J. Pharmacol. Expt. Ther. 271(2):1074-1079, 1994.
 

Posner, GH, MC White, P Dolan, T W Kensler, S Yukihiro, SE Guggino. 1a,25-dihydroxyvitamin D3 hybrid analogs with structural changes at both the A-ring and the C,D-ring side-chain I. Bioorg. Med. Chem. Lett. 4(24):2919-2924, 1994.
 

Yukihiro, S, GH Posner, SE Guggino. Vitamin D3 analogs stimulate calcium currents in rat osteosarcoma cells. J. Biol. Chem. 269(39):23889-23893, 1994.
 

Lin, M, K MacLeod, SE Guggino. Heat stable toxin from Escherichia coli activates chloride current via cGMP-dependent protein kinase. Cell. Physiol. Biochem.119(5):1-8, 1995.
 
Posner, GH, JK Lee, Z Li, K Takeuchi, SE Guggino, P Dolan, TW Kensler.  1a,25-Dihydroxyvitamin D3 Hybrid Analogs with Structural Changes at both the A-Ring and the C,D-Ring-Side-Chain II. Bioorg. Med. Chem. Lett. 5(18):2163-2168, 1995.
 
Posner, GH, Z Li, MC White, V Vinader, K Takeuchi, SE Guggino, P Dolan, TW Kensler.  1a,25-Dihydroxyvitamin D3 Analogues Featuring Aromatic and Hetero-aromatic Rings:  Design, Synthesis, and Preliminary Biological Testing.  J. Med. Chem. 38(22): 4529-4537, 1995. 
 
Lo, H, S Kadiyala, SE Guggino, KW Leong. Poly (L-lactic acid) foams with cell seedling and controlled-release capacity.  J. Biomed. Mater. Res. 30(4):475-484, 1996.
 
Takeuchi, K, SE Guggino. 24,25-(OH)2 vitamin D3 inhibits 1?,25-(OH)2 vitamin D3 and testosterone potentiation of calcium channels in osteosarcoma cells. J. Biol. Chem. 271(52):33335-33343, 1996.
 
Ding, C, ED Potter, W Qiu, SL Coon, MA Levine, SE Guggino. Cloning and widespread distribution of the cyclic nucleotide-gated cation channel. Am. J. Physiol. 272 (Cell Physiol. 41):C1335-C1344, 1997.
 

Publications Next

615 N. Wolfe Street, Baltimore, MD 21205