GENE THERAPY VECTOR

 CLINICAL CENTER GENOTYPING CENTER
Information regarding Cystic Fibrosis, the types of research being performed to finds its cure. Learn more about gene therapy, and treatments for Cystic Fibrosis as well as volunteering opportunities.
The Center has many research laboratories dedicated to finding a cure for Cystic Fibrosis. Meet the different lab directors, their lab members and the laboratories particular focus.
A complete list of publications from the Centers lab directors that are related to Cystic Fibrosis.
Apply for open positions at the Cystic Fibrosis Research Development Center.
Visit other websites of organizations and associations affiliated with Cystic Fibrosis.
Letter from the Director addressing the Centers continued plan for the future.
 
 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
 
 

 
 

Sandra Elizabeth Guggino

Sandra Home | Research Interests | Publications | Book Chapters | Lab Members

 

 

Sandra Elizabeth Guggino
Associate Professor
Division of Gastroenterology
Department of Medicine
The Johns Hopkins University School of Medicine
929 Ross Research Building
720 Rutland Avenue
Baltimore, MD 21205
Email: sguggino@jhmi.edu 

 

Sandra Guggino
 

        
  Publications
 

Qiu, W, B Lee, W Xu, M Lancaster, SE Guggino. Cyclic-nucleotide gated cation channels mediate amiloride-insensitive sodium and calcium influx in rat colon. Am. J. Physiol. Cell 278(2):C336-C343, 2000.
 
Silva, IV, C Blaisdell, SE Guggino, WB Guggino. PTH regulates the expression of the ClC-5 chloride channel in the kidney. Am. J. Physiol. Cell 278(2):F238-245, 2000.
 

Wang, X-T, Y Nagaba, S Nagaba, S Leung, W Qiu, P Zhao, SE Guggino. Cardiac L-type calcium channel a1–subunit is increased by cyclic adenosine monophosphate: messenger RNA and protein expression in intact bone. J. Bone and Min. Res. 5(7):1275-1285, 2000.
 

Wang, X.T, Y Nagaba, HS Cross, F Wrba, L Zhang, SE Guggino. The mRNA of L-type calcium channel elevated in colon cancer: protein distribution in normal and cancerous colon. Am. J. Path. 157(5):1549-1562, 2000.
 
Wang, SS, O Devuyst, PJ Courtoy, XT Wang, H Wang, Y Wang, RJ Thakker, SE Guggino, WB Guggino. Mice lacking renal chloride channel ClC-5 are a model for Dent’s disease, an X-linked Fanconi syndrome with nephrolithiasis. Human Molecular Genetics 9(20):2937-2945, 2000.
 

Kadiyala S, S Nagaba , K Takeuchi, S Yukihiro, W Qiu , ST Eyes, M Uskokovic, G Posner, SG Reddy and SE Guggino. Metabolites and analogs of 1a,25-dihydroxyvitamin D3: Evaluation of action in bone. Steroids 66(3-5):347-355, 2001.
 

Norlin, A, LN Lu, SE Guggino, MA Matthay, HG Folkesson. Contribution of Amiloride-insensitive pathways to alveolar fluid clearance in adult rats. J. Applied Physiol. 90(4):1489-1496, 2001.
 

Zhao, P, X-T. Wang, XM Zhang , V Cebotaru, L Cebotaru, G Gou, M Morales and SE Guggino. Tubular and Cellular localization of the Cardiac L-type calcium channel in rat kidney. Kidney Int. (4):1393-406, 2002.
 
Fischer, AC, Beck, SE; Smith, CI; Laube, BL; Askin, FB; Guggino, SE; Adams, RJ; Flotte, TR; Guggino, WB. Successful Transgene Expression with Serial Doses of Aerosolized rAAV2 Vectors in Rhesus macaques. Mol Ther. 8(6):918-26, 2003.
 
Glunde K, SE Guggino, Y. Ichikawa, and Z. M. Bhujwalla. A Novel Method of Imaging Lysosomes in Living Human Mammary Epithelial Cells. Molecular Imaging 2(1):24-36,2003.
 

Glunde, K SE Guggino, M Solaiyappan, AP Pathak, Yachikawa ZM Bhjwalla. Extracellular acidification alters lysosomal trafficking in human breast cancer cells. Neoplasia 5(6): 533-545 2003.
 
Nascimento DS, Reis CU, Goldenberg RC, Ortiga-Carvalho TM, Pazos-Moura CC, Guggino SE, Guggino WB, Morales MM. Estrogen modulates ClC-2 chloride channel gene expression in rat kidney. Pflugers Arch. 446(5):593-9, 2003.
 

Publications Next

615 N. Wolfe Street, Baltimore, MD 21205